How Molecular Hydrogen assists with Parkinson’s & other Neurodegenerative Disorders
Parkinson’s is a nerve disease that is caused by the lack of dopamine in the brain. Major symptoms include tremor of hands and feet, slower ‘shuffling’ movement, muscle stiffness and dementia may also develop as a secondary condition. The onset of symptoms tend to arise around the 40s~50’s, and it is categorised by modern medicine as an irreversible disease. Research projects have been underway in Japan and USA to study whether Molecular Hydrogen ~ a potent Antioxidant, has the ability to supress progression of Parkinson’s and other Neurodegerative diseases. This page lists some important research papers on the relationship of Hydrogen and Parkinson’s/brain diseases. (Source: https://www.ncbi.nlm.nih.gov)
Dementia treatment with Hydrogen Gas Inhalation
Degenerative Brain disorders occur due to damage of brain tissue and cell damage, which for the most part is induced by calcification and oxidative stress. Neurodegenerative diseases are divided into two types: one impacting movement, such as cerebellar ataxia, and the other affecting memory and is related to dementia. Study found that inhaling molecular hydrogen deter the decline of memory and learning ability. (Department of Neurosurgery & Brain and nerve Research Laboratory, the first affiliated hospital of Soochow university, Suzhou, Jiangsu Province, China)
Molecular Hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through mitohormesis
Inhalation of Molecular Hydrogen (H2) gas ameliorates oxidative stress-induced acute injuries in the brain. H2 also prevents chronic Neurodegenerative diseases including Parkinson’s disease. (Tokyo Metropolitan Institute of Gerontology, Japan, May 3rd, 2017)
Molecular Hydrogen as Therapeutic medical gas for Neurodegenerative and other diseases
Effects of Molecular Hydrogen on various diseases have been documented in 63 disease models including human diseases in the past four and a half years. intestinal bacteria in humans and rodents produce a large amount of hydrogen gas, but an addition of a small amount of hydrogen exhibits marked effects. (Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Japan, June 8th, 2012)
Ingestion of hydrogen gas can improve neurological function outcome in the spontaneously hypertensive stroke
Hydrogen gas decreased oxidative stress (8-OHdG, 4-HNE and nitrotyrosine) and exerted neuroprotective effects (improvement of neurological score and reduction in infarct and hemorrhagic volumes) and also reduced MMP-9 activation in a middle cerebral artery occlusion model.
Medical hydrogen gas for stroke therapy: summary of progress 2015-2016
Stroke is a Cerebrovascular disease with high mortality and morbidity. Despite extensive research, there are to date, a very limited number of therapeutic approaches suitable for treatment of stroke patients. Mounting evidence demonstrates that gases such as ozone, hydrogen and hydrogen sulfide are able to provide neuro-protection after stroke. (Discipline of Neuroscience, Department of Anatomy, Shanghai Jia Tong University School of Medicine Jun 30th, 2017)
Hydrogen gas inhalation treatment in acute cerebral infarction: a randomized controlled clinical study on safety and neuroprotection
Molecular Hydrogen (H2) acts as a therapeutic antioxidant. Inhalation of H2 gas (1-4%) was effective for the improvement of cerebral infarction in multiple animal experiments. The H2 group showed no significant adverse effects with improvements in oxygen saturation. H2 treatment was safe and effective in patients with acute cerebral infarction. These results suggested a potential for widespread and general application of H2 gas. (Department of Neurosurgery, Nishijima Hospital, Numazu-city, Shizuoka-ken, Japan Jun 29th, 2017)
Molecular Hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis (a.k.a Mitochondrial Hormesis)
Inhalation of Molecular Hydrogen (H2) gas ameliorates oxidative stress-induced acute injuries in the brain. It prevents chronic neurodegenerative diseases including Parkinson’s disease in animal and clinical studies. (Tokyo Metropolitan Institute of Gerontology, May 3rd, 2017)
