The research studies listed below cover a range of investigations into the potential therapeutic effects of hydrogen-rich substances on various health conditions. For example, studies by Chen et al. (2015) and Ge et al. (2013) explore how hydrogen-rich treatments can attenuate neuropathic pain by targeting oxidative stress and inhibiting the activation of spinal astrocytes and microglia in rat models. Similarly, research by Kawaguchi et al. (2014) and Zhao et al. (2013) delves into the molecular mechanisms through which hydrogen may alleviate neuropathic pain in mice and aplastic anemia in vivo, respectively. Other studies, such as those by Sakai et al. (2014) and Tsubone et al. (2013), investigate the potential benefits of consuming hydrogen-rich water on vascular endothelial function and oxidative metabolites in serum, respectively. Additionally, investigations by Guan et al. (2015) and Li et al. (2013) explore the effects of hydrogen on placental function and nephrotoxicity, highlighting the diverse range of health conditions being studied in relation to hydrogen-rich substances.
449.Chen, Y., et al., H Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. Inflammation, 2015.
450.Chen, Q., et al., Hydrogen-rich saline attenuated neuropathic pain by reducing oxidative stress. Can J Neurol Sci, 2013. 40(6): p. 857-63.
451.Ge, Y., et al., Intrathecal Infusion of Hydrogen-Rich Normal Saline Attenuates Neuropathic Pain via Inhibition of Activation of Spinal Astrocytes and Microglia in Rats. PLoS One, 2014. 9(5): p. e97436.
452.Guan, Z., et al., Effects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells. Arch Gynecol Obstet, 2015.
453.Kawaguchi, M., et al., Molecular hydrogen attenuates neuropathic pain in mice. PLoS One, 2014. 9(6): p. e100352.
454.Koseki, S. and K. Itoh, Fundamental properties of electrolyzed water. Journal of the Japanese Society for Food Science and Technology-Nippon Shokuhin Kagaku Kogaku Kaishi, 2000. 47(5): p. 390-393.
455.Li, F.Y., et al., Consumption of hydrogen-rich water protects against ferric nitrilotriacetate-induced nephrotoxicity and early tumor promotional events in rats. Food Chem Toxicol, 2013. 61: p. 248-54.
456.Morita, C., T. Nishida, and K. Ito, Biological toxicity of acid electrolyzed functional water: effect of oral administration on mouse digestive tract and changes in body weight. Arch Oral Biol, 2011. 56(4): p. 359-66.
457.Sakai, T., et al., Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function. Vasc Health Risk Manag, 2014. 10: p. 591-7.
458.Tsubone, H., et al., Effect of Treadmill Exercise and Hydrogen-rich Water Intake on Serum Oxidative and Anti-oxidative Metabolites in Serum of Thoroughbred Horses. J Equine Sci, 2013. 24(1): p. 1-8.
459.Wang, W.N., et al., [Regulative effects of hydrogen-rich medium on monocytic adhesion and vascular endothelial permeability]. Zhonghua Yi Xue Za Zhi, 2013. 93(43): p. 3467-9.
460.Yahagi, N., et al., Effect of electrolyzed water on wound healing. Artificial Organs, 2000. 24(12): p. 984-987.
461.Zhao, S., et al., Therapeutic effects of hydrogen-rich solution on aplastic anemia in vivo. Cell Physiol Biochem, 2013. 32(3): p. 549-60.
449.Chen, Y., et al., H Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. Inflammation, 2015.
450.Chen, Q., et al., Hydrogen-rich saline attenuated neuropathic pain by reducing oxidative stress. Can J Neurol Sci, 2013. 40(6): p. 857-63.
451.Ge, Y., et al., Intrathecal Infusion of Hydrogen-Rich Normal Saline Attenuates Neuropathic Pain via Inhibition of Activation of Spinal Astrocytes and Microglia in Rats. PLoS One, 2014. 9(5): p. e97436.
452.Guan, Z., et al., Effects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells. Arch Gynecol Obstet, 2015.
453.Kawaguchi, M., et al., Molecular hydrogen attenuates neuropathic pain in mice. PLoS One, 2014. 9(6): p. e100352.
454.Koseki, S. and K. Itoh, Fundamental properties of electrolyzed water. Journal of the Japanese Society for Food Science and Technology-Nippon Shokuhin Kagaku Kogaku Kaishi, 2000. 47(5): p. 390-393.
455.Li, F.Y., et al., Consumption of hydrogen-rich water protects against ferric nitrilotriacetate-induced nephrotoxicity and early tumor promotional events in rats. Food Chem Toxicol, 2013. 61: p. 248-54.
456.Morita, C., T. Nishida, and K. Ito, Biological toxicity of acid electrolyzed functional water: effect of oral administration on mouse digestive tract and changes in body weight. Arch Oral Biol, 2011. 56(4): p. 359-66.
457.Sakai, T., et al., Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function. Vasc Health Risk Manag, 2014. 10: p. 591-7.
458.Tsubone, H., et al., Effect of Treadmill Exercise and Hydrogen-rich Water Intake on Serum Oxidative and Anti-oxidative Metabolites in Serum of Thoroughbred Horses. J Equine Sci, 2013. 24(1): p. 1-8.
459.Wang, W.N., et al., [Regulative effects of hydrogen-rich medium on monocytic adhesion and vascular endothelial permeability]. Zhonghua Yi Xue Za Zhi, 2013. 93(43): p. 3467-9.
460.Yahagi, N., et al., Effect of electrolyzed water on wound healing. Artificial Organs, 2000. 24(12): p. 984-987.
461.Zhao, S., et al., Therapeutic effects of hydrogen-rich solution on aplastic anemia in vivo.Cell Physiol Biochem, 2013. 32(3): p. 549-60.
