Kidney Diseases and Hydrogen Therapy
How Molecular Hydrogen assists with Kidney-related diseases
Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients…
Recent clinical studies have shown that molecular hydrogen is biologically active as an anti-inflammatory agent among chronic dialysis treatment and powerful oxidative stress. (CDC Center for Disease Control and Prevention)
Hydrogen Alleviates Renal injury through reducing Iron overload
Iron-induced oxidative stress has been found to be pivotal in the pathogenesis of kidney disorders. Recent studies have indicated H₂ can be used as an antioxidant to protect cells. In conclusion, Hydrogen may attenuate CIH-induced renal injury at least partially via inhibiting renal iron-overload. (Department of Physiology, Hebei University of Chinese Medicine)
Therapeutic effects of Molecular Hydrogen in post-operative kidney transplants
The incidence of chronic graft‐versus‐host disease (cGVHD) is rising recent years, which has been the leading cause of mortality post transplantation. The study shows that molecular hydrogen has anti‐inflammatory, anti‐fibrosis and antioxidant effects.
Nano-particle Hydrogen for acute kidney damage & myocardial infarction:
Studies suggest possible therapeutic effects of molecular hydrogen in aspects of emergency and critical care medicine, such as contrast-induced acute kidney injury, acute myocardial infarction, cardio-pulmonary arrest syndrome, and hemorrhagic shock. (Department of Cardiology, Keio University School of Medicine, Tokyo, Japan, Oct 24th 2017)
Hydrogen molecules (H2) improves perfusion-recovery via antioxidant effects in Peripheral Arterial Disease
Reactive Oxygen Species (ROS) impairs neovascularisation and perfusion-recovery following limb ischemia in patients with Peripheral Prterial Disease (PAD). Hydrogen molecules (H2) possesses an antioxidant that has been reported to neutralise cytotoxic ROS. H2 gas increases angiogenesis and arteriogenesis and subsequently improves perfusion-recovery in a mouse PAD model via reduction of ROS levels.
