The research articles below explore the effects of hydrogen-rich water and electrolysed-reduced water on biological systems. Key findings include enhanced antioxidant effects, protection against oxidative damage, increased resistance to environmental stresses, and potential lifespan extension in organisms like Caenorhabditis elegans. These studies highlight the potential benefits of these water types in reducing oxidative stress and promoting overall health.
1.Akhavan, O., et al., Hydrogen-rich water for green reduction of graphene oxide suspensions. International Journal of Hydrogen Energy, 2015. 40(16): p. 5553-5560.
2.Berjak, P., et al., Cathodic amelioration of the adverse effects of oxidative stress accompanying procedures necessary for cryopreservation of embryonic axes of recalcitrant-seeded species. Seed Science Research, 2011. 21(3): p. 187-203.
3.Hanaoka, K., Antioxidant effects of reduced water produced by electrolysis of sodium chloride solutions. Journal of Applied Electrochemistry, 2001. 31(12): p. 1307-1313.
4.Hanaoka, K., et al., The mechanism of the enhanced antioxidant effects against superoxide anion radicals of reduced water produced by electrolysis.Biophysical Chemistry, 2004. 107(1): p. 71-82.
5.Hiraoka, A., et al., In Vitro Physicochemical Properties of Neutral Aqueous Solution Systems (Water Products as Drinks) Containing Hydrogen Gas, 2-Carboxyethyl Germanium Sesquioxide, and Platinum Nanocolloid as Additives. Journal of Health Science, 2010. 56(2): p. 167-174.
6.Hiraoka, A., et al., Studies on the properties and real existence of aqueous solution systems that are assumed to have antioxidant activities by the action of “active hydrogen”‘. Journal of Health Science, 2004. 50(5): p. 456-465.
7.Kato, S., D. Matsuoka, and N. Miwa, Antioxidant activities of nano-bubble hydrogen-dissolved water assessed by ESR and 2, 2′-bipyridyl methods.Materials Science and Engineering:, 2015. C 53: p. 7-10.
8.Lee, M.Y., et al., Electrolyzed-reduced water protects against oxidative damage to DNA, RNA, and protein. Appl Biochem Biotechnol, 2006. 135(2): p. 133-44.
9.Ohsawa, I., et al., Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med, 2007. 13(6): p. 688-694.
10.Ohta, S., Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications. Methods Enzymol, 2015. 555: p. 289-317.
11.Park, E.J., et al., Protective effect of electrolyzed reduced water on the paraquat-induced oxidative damage of human lymphocyte DNA. Journal of the Korean Society for Applied Biological Chemistry, 2005. 48(2): p. 155-160.
12.Park, S.K., et al., Electrolyzed-reduced water confers increased resistance to environmental stresses. Molecular & Cellular Toxicology, 2012. 8(3): p. 241-247.
13.Park, S.K. and S.K. Park, Electrolyzed-reduced water increases resistance to oxidative stress, fertility, and lifespan via insulin/IGF-1-like signal in C. elegans. Biol Res, 2013. 46(2): p. 147-52.
14.Penders, J., R. Kissner, and W.H. Koppenol, ONOOH does not react with H2. Free Radic Biol Med, 2014.
15.Qian, L., et al., Administration of hydrogen-rich saline protects mice from lethal acute graft-versus-host disease (aGVHD). Transplantation, 2013. 95(5): p. 658-62.
16.Shi, Q.H., et al., Hydrogen Therapy Reduces Oxidative Stress-associated Risks Following Acute and Chronic Exposure to High-altitude Environment.Biomed Environ Sci, 2015. 28(3): p. 239-41.
17.Shirahata, S., et al., Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage. Biochemical and Biophysical Research Communications, 1997. 234(1): p. 269-274.
18.Yan, H., et al., Mechanism of the lifespan extension of Caenorhabditis elegans by electrolyzed reduced water–participation of Pt nanoparticles.Bioscience, Biotechnology, and Biochemistry, 2011. 75(7): p. 1295-9.
19.Yan, H., et al., electrolyzed reduced water prolongs caenorhabditis elegans lifespan, in Animal Cell Technology: Basic & Applied Aspects. 2010, Springer Netherlands. p. 289-293.
20.Yan, H.X., et al., Extension of the Lifespan of Caenorhabditis elegans by the Use of Electrolyzed Reduced Water. Bioscience Biotechnology and Biochemistry, 2010. 74(10): p. 2011-2015.
21.Yanagihara, T., et al., Electrolyzed hydrogen-saturated water for drinking use elicits an antioxidative effect: a feeding test with rats. Biosci Biotechnol Biochem, 2005. 69(10): p. 1985-7.
